产品货号:
Z29354
中文名称:
ULK3抗体
英文名称:
Anti-ULK3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ULK3 Antibody |
指标别名 | unc-51 like kinase 3;ULK3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ULK3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ULK3 antibody was raised against a 19 amino acid peptide near the center of human ULK3.The immunogen is located within amino acids 230 - 280 of ULK3. |
计算分子量 | 53kDa |
成分 | ULK3 antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ULK3 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | ULK3 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1).Knockout of ULK genes results in a severe defect in the autophagy pathway (2).ULK3,like the other Unc-51-like kinases such as ULK1,ULK2 and ULK4,is highly conserved among eukaryotes (3).ULK3 has been shown to be a positive regulator of the Hedgehog signaling pathway by enhancing GLI1 and GLI2 transcriptional activity (4).Furthermore,ULK3 can also interact with SUFU,a protein required for the negative regulation of GLI proteins;this interaction blocks the autophosphorylation of ULK3 and blocks its ability to regulate the GLI proteins (5). |
Uniprot ID | Q6PHR2 |
基因名全称 | Unc-51 like kinase 3 |
蛋白名全称 | Unc-51 like kinase 3 |
推荐稀释比 | ULK3 antibody can be used for detection of ULK3 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for Immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索:ULK3抗体,ULK3多抗,Anti-ULK3 Antibody